WHO data to 27 Sep 2026 · updates automatically
As of 27 September 2026, 46,582 confirmed mpox (monkeypox) cases and 111 deaths have been reported in 21 countries and territories in North America, 24.1% of the world total. The most affected are United States (37,929), Mexico (5,069), Canada (2,381). In August 2026 countries in North America reported 1 new cases, compared with 9 the month before.
Mpox map: North America
Map of confirmed mpox cases in North America.
New cases per month: North America
By month of report to WHO; hatched months are still being reported
Monthly new confirmed mpox cases in North America.
Total confirmed cases: North America
Cumulative since 2022
Cumulative confirmed mpox cases in North America.
Mpox cases by country in North America
21 countries and territories with confirmed cases. Click a column to sort.
| # | Country | Cases | Deaths | Per 1M | Last 90 d |
|---|---|---|---|---|---|
| 1 | United States | 37,929 | 63 | 111.0 | 603 |
| 2 | Mexico | 5,069 | 42 | 38.4 | 6 |
| 3 | Canada | 2,381 | 0 | 57.2 | 2 |
| 4 | Guatemala | 411 | 2 | 22.0 | 0 |
| 5 | Panama | 258 | 1 | 56.4 | 0 |
| 6 | Costa Rica | 235 | 1 | 45.6 | 2 |
| 7 | El Salvador | 106 | 0 | 16.7 | 0 |
| 8 | Dominican Republic | 83 | 1 | 7.2 | 0 |
| 9 | Honduras | 53 | 0 | 4.8 | 0 |
| 10 | Jamaica | 22 | 0 | 7.8 | 0 |
| 11 | Cuba | 8 | 1 | 0.7 | 0 |
| 12 | Martinique | 7 | 0 | 20.0 | 0 |
| 13 | Trinidad and Tobago | 4 | 0 | 2.9 | 0 |
| 14 | Bahamas | 4 | 0 | 9.9 | 0 |
| 15 | Curaçao | 3 | 0 | 19.2 | 0 |
| 16 | Aruba | 3 | 0 | 27.6 | 0 |
| 17 | Greenland | 2 | 0 | 35.2 | 0 |
| 18 | Guadeloupe | 1 | 0 | 2.6 | 0 |
| 19 | Barbados | 1 | 0 | 3.5 | 0 |
| 20 | Bermuda | 1 | 0 | 15.5 | 0 |
| 21 | Saint Martin | 1 | 0 | 40.1 | 0 |
Mpox in North America: frequently asked questions
How many mpox cases are there in North America?
21 countries and territories in North America have reported 46,582 laboratory-confirmed mpox cases to WHO as of 27 September 2026, 24.1% of all cases worldwide.
Which countries in North America have the most mpox cases?
The countries with the most confirmed cases are United States (37,929), Mexico (5,069), Canada (2,381), Guatemala (411), Panama (258). Every country is listed in the table on this page, with a link to its own tracker.
Is mpox increasing in North America?
Countries in North America reported 1 new cases in August 2026, down from 9 in July. Over the last 90 days of data there were 613 new cases, against 412 in the previous 90 days.
How many people have died from mpox in North America?
111 mpox deaths have been confirmed in North America (0.24% of confirmed cases), the most in United States (63).
Which countries in North America have reported clade Ib mpox?
3 countries in North America have reported clade Ib: United States, Canada, Costa Rica.
Where does this data come from?
Case and death counts are laboratory-confirmed figures reported by each country to the World Health Organization. WHO publishes about once a month, so figures can be several weeks behind; this page updates automatically when new data is released.