CDC data to 7 Nov 2026 (week 44) · provisional · updates weekly
As of the week ending 7 November 2026, Illinois has reported 46 mpox (monkeypox) cases in 2026, compared with 202 by the same point in 2025 and 213 in all of 2025. That ranks 7th among US states and territories, or 3.6 cases per million residents. In the last 8 weeks 23 cases were added, against 11 in the 8 weeks before.
Weekly mpox cases: Illinois
Cases added each week, 2025–2026 (CDC, provisional)
Weekly mpox cases in Illinois.
US mpox cases by state
1,500 cases in 2026 so far vs 2,128 by this point in 2025
| State | 2026 to date | Per 1M | 2025 same period | Latest week |
|---|---|---|---|---|
| California | 513 | 13.1 | 352 | 21 |
| New York | 220 | 11.1 | 379 | 9 |
| Florida | 116 | 5.3 | 92 | 2 |
| Massachusetts | 53 | 7.6 | 47 | 0 |
| Nevada | 51 | 16.2 | 6 | 3 |
| Arizona | 49 | 6.7 | 0 | 4 |
| Illinois | 46 | 3.6 | 202 | 6 |
| Colorado | 45 | 7.7 | 21 | 1 |
| Ohio | 35 | 3.0 | 23 | 0 |
| Texas | 33 | 1.1 | 260 | 1 |
| Georgia | 27 | 2.5 | 103 | 0 |
| Rhode Island | 27 | 24.6 | 5 | 3 |
| Minnesota | 25 | 4.4 | 18 | 0 |
| Pennsylvania | 25 | 1.9 | 45 | 6 |
| New Jersey | 23 | 2.5 | 30 | 0 |
| Maryland | 22 | 3.6 | 69 | 0 |
| Virginia | 20 | 2.3 | 32 | 1 |
| North Carolina | 18 | 1.7 | 34 | 0 |
| Connecticut | 15 | 4.2 | 13 | 1 |
| Kentucky | 12 | 2.7 | 10 | 2 |
| Tennessee | 11 | 1.6 | 48 | 0 |
| Indiana | 10 | 1.5 | 10 | 0 |
| Oregon | 10 | 2.4 | 19 | 0 |
| Washington | 10 | 1.3 | 123 | 0 |
| South Carolina | 9 | 1.7 | 12 | 5 |
| Wisconsin | 7 | 1.2 | 6 | 1 |
| Maine | 6 | 4.4 | 0 | 0 |
| Missouri | 6 | 1.0 | 13 | 0 |
| Alabama | 5 | 1.0 | 15 | 0 |
| Michigan | 4 | 0.4 | 20 | 0 |
| New Mexico | 4 | 1.9 | 2 | 0 |
| Utah | 4 | 1.2 | 1 | 0 |
| Idaho | 3 | 1.6 | 2 | 0 |
| Puerto Rico | 3 | 0.9 | 9 | 0 |
| Mississippi | 2 | 0.7 | 0 | 0 |
| Oklahoma | 2 | 0.5 | 8 | 0 |
| Alaska | 1 | 1.4 | 1 | 0 |
| Kansas | 1 | 0.3 | 2 | 0 |
| Montana | 1 | 0.9 | 0 | 0 |
| New Hampshire | 1 | 0.7 | 4 | 0 |
| Arkansas | 0 | 0.0 | 0 | 0 |
| Delaware | 0 | 0.0 | 0 | 0 |
| District Of Columbia | 0 | 0.0 | 0 | 0 |
| Hawaii | 0 | 0.0 | 1 | 0 |
| Iowa | 0 | 0.0 | 2 | 0 |
| Louisiana | 0 | 0.0 | 43 | 0 |
| Nebraska | 0 | 0.0 | 1 | 0 |
| North Dakota | 0 | 0.0 | 0 | 0 |
| South Dakota | 0 | 0.0 | 0 | 0 |
| Vermont | 0 | 0.0 | 1 | 0 |
| West Virginia | 0 | 0.0 | 1 | 0 |
| Wyoming | 0 | 0.0 | 0 | 0 |
Mpox in Illinois: frequently asked questions
How many mpox cases are there in Illinois in 2026?
Illinois has reported 46 mpox cases in 2026 as of the week ending 7 November 2026, according to provisional CDC data, 77% fewer than the 202 reported by the same point in 2025.
Are mpox cases rising in Illinois?
23 cases were added in the last 8 weeks, up from 11 in the previous 8 weeks. The weekly chart on this page shows the full trend since January 2025.
How many mpox cases were there in Illinois in 2025?
Illinois reported 213 mpox cases in 2025 (CDC provisional year-end total).
How does Illinois compare with other states?
Illinois ranks 7th of 52 US states and territories by mpox cases in 2026, with 3.6 cases per million residents against a national rate of about 4.4. The United States as a whole has reported 1,500 cases in 2026.
Where can I get an mpox vaccine in Illinois?
The JYNNEOS (MVA-BN) vaccine is available in the US through many doctors, pharmacies, sexual health clinics and local health departments. It is given as two doses four weeks apart. Contact your healthcare provider or the Illinois health department to find a location near you.
Where does the Illinois mpox data come from?
Figures come from the CDC National Notifiable Diseases Surveillance System (NNDSS) weekly tables and are provisional: cases can be added later as reports arrive. This page checks for new data every 2 hours.